824 Dourine. 



from the urethra. In infrequent cases the swollen glans appears 

 of higher temperature and more sensitive. The border of the 

 urethral opening is also frequently swollen, slightly reddened 

 and the mucous membrane protrudes slightly (especially in 

 jacks). Later lentil to pea-sized, yellowish-red nodules on an 

 infiltrated base develop, sometimes singly, at other times in 

 groups, on the mucous membrane of the urethra in the vicinity 

 of the urethral opening, also on the glans and on the body 

 of the penis, and change into round, flat ulcers in 12 to 36 hours; 

 these usually heal after a time, leaving behind roundish white 

 spots. In some cases however they may persist for a long 

 time, and even enlarge, after which their base is lardaceous, 

 their borders raised, and on final healing prominent scars re- 

 main. 



During the development of these changes the animals mani- 

 fest a continuous desire to urinate, but they pass only small 

 quantities of urine and nervously raise one of the hind legs 

 or arch their backs. Besides this frequent erections of the 

 penis are observed and the animals usually show an increased 

 sexual desire. 



In mares the first manifestations consist in an edematous 

 swelling of the vulva, discharge from the vagina, also redden- 

 ing and inflammatory swelling of the vaginal mucous mem- 

 ))rane. The labia of the vulva usually appear swollen on both 

 sides, frequently however not uniformly; at the same time they 

 are dense, elastic, not painful, and frequently covered with 

 non-pigmented spots, similar to those sometimes occurring in 

 the vicinity of the rectum (so-called toad spots). Sometimes 

 the clitoris is swollen, so that it protrudes from the lower 

 gaping opening in the vulva. The mucous membrane of the 

 vagina is loosened, shows dark red spots on a reddish-yellow 

 base and is sometimes thickened into gelatinous, quivering, 

 longitudinal pads. The mucous follicles are also swollen, 

 especially in the superior commissure, and in the vicinity of 

 the clitoris gelatinously translucent, and may be felt as millet- 

 seed-sized, rarely larger nodules. The nodules may later break 

 down, whereupon in their place small round ulcers, with sharp 

 Ijorders and yellowish bases appear. The ulcers finally heal, 

 either without leaving any trace, or in their places light yellow 

 spots may remain for a time (proliferated epithelium) (Fig. 

 145). Besides the nodules, pea-sized vesicles may develop ex- 

 ceptionally on the mucous membrane of the vagina and on the 

 vulva, in rare cases also in the surrounding portions of the 

 skin, these contain a yellow serous fluid, and similar small ulcers 

 develop after they burst. 



In severe cases the ulcerations increase in size, their bases 

 becoming covered mth necrotic tissue and the dark red borders 

 shelving an elevated swelling. They heal very slowly, and 

 in their places round, smooth scars remain for a long time. 

 Meanwhile the discharge from the vagina increases; first it 



