Diagnosis, Treatment. gg;^ 



conditions of the white blood corpuscles in stained specimens 

 frequently affords sufficient grounds for a differential diagnosis. 

 A relatively uniform increase of all representatives of white 

 blood corpuscles and the absence of unripe forms of cells are 

 met with in simple leucocytosis. The mononuclear leucocytes 

 however appear to gain the upper hand even in certain cases 

 of leucocytosis, which was indicated by the observations of 

 Skiba. 



Treatment. Very few experiments have been attempted in 

 this respect. Ellermann & Bang observed recovery in one case 

 after treatment with arsenic; it cannot however be decided 

 whether this did not represent an accidental spontaneous re- 

 covery. The Rontgen treatment proved unsatisfactory in an- 

 other case. 



Literature. Eber, Leipz. B., 1907/08. 54. — Ellermann & Bau^-, Cbl. f. 

 Bakt., 1908. XLVI. (Orig.), .595 (Lit.); Z. f. Hyg., 1909. LXIII. 231. — Hirsch- 

 fekl & Jacobv, Z. f. kl. Med., 1909. LXIX. 1 (Lit.). — Skiba, D. t. W., 1909. 

 405 (Lit.). 



5. Pseudo-Leukemia. Pseudo-Leukaemia. 



(Hodghui's Disease, Aleukemic Lymphadenia, Suhlymphatic 

 Leukemia [Helly]; Lympliadenia [Vircliow]; Pseudo- 

 leukaemia lymphatica [Piiikus].) 



By pseudo-leukemia is understood a chronic affection in 

 which the blood-forming organs show the same changes as in 

 leukemia. The increase of white blood corpuscles in the blood 

 is however absent. 



Occurrence. Up to the present cases have been observed 

 in horses, dogs, cattle and in a cat (de Does). The disease 

 occurs more frequently than leukemia for which it is frequently 

 mistaken. Leukemia of chickens is in about half of the cases 

 also manifested by the symptoms of pseudo-leukemia (see p. 

 877). 



Etiology. The absence of an increase of white blood cor- 

 puscles constitutes the only important difference between 

 leukemia and pseudo-leukemia; otherwise the anatomical 

 changes, as well as the clinical symptoms are almost identical. 

 As a matter of fact the h^nphocy'tes may be present in a higher 

 percentage than normally, although the total number of the 

 white blood corpuscles remains comparatively normal. This 

 phenomenon occurs in pseudo-leukemia of man, was also ob- 

 served by A. Zimmermann in a cow, by Jaeger in a dog, and 

 by Hirsciifeld & Jacoby in the pseudo-leukemic stage of chicken 

 leukemia. 



Based on this correspondence the view is greatly supported, 

 according to w^hich pseudo-leukemia is held to be identical in 



