Anatomical Changes. Synijjtoms. 557 



causing cirrhosis. In some cases the embryos in the lungs set 

 up broncho-pneumonia and even pleurisy. 



Anatomical Changes. In the acute stage the liver is more 

 or less enlarged, although there may be no enlargement in some 

 cases. Its serous membrane is dull and may be covered with a 

 hoar-like fibrinous layer. In many cases the surface of the 

 organ appears nodular and the apex of each nodule shows a 

 minute opening. The liver itself has a speckled, mosaic-like 

 appearance (mosaic liver or trout liver) on account of the va- 

 riation of color of the lobules. Some of these are black or 

 blackish-red and others are pale red or grayish-brown. The 

 darkly colored lobules are enlarged. The consistency of the 

 organ is soft, and the tissue is easily broken down. Close ex- 

 amination sometimes shows within the dark-colored lobules 

 yellow points or transparent acephalic cysts measuring three 

 to four mm. in length, by one to two mm. broad. In the later 

 stages there can be seen burrows in the liver tissue which at 

 first were filled with blood and afterwards become yellowish- 

 gray in color as a result of degeneration of the injured tissue, 

 and the outpouring of an exudate. These burrows are some- 

 times sinous and sometimes wider at one end. 



Microscopic examination reveals the presence of cysticerci in the little pools 

 of blood and cellular infiltration in the neighborhood and in the interlobular con- 

 nective tissue, especially at the angles of the lobules. Finally there is compression 

 and partial degeneration of the liver tissue. 



Not rarely there is acute peritonitis or there may be liquid 

 blood in the peritoneum. In this blood may be seen numbers 

 of very minute pale-colored bodies (young cysticerci). 



In chronic cases there is more or less chronic interstitial 

 hepatitis and shrinkage of the new connective tissue. 



Symptoms. The symptoms of acute cysticercosis of the 

 liver set in a few days after infection. This has been proved 

 by the feeding experiments of Kiichenmeister, Leisering, 

 Leuckart, Baillet and Railliet. A kid infected experimentally 

 l)y Railliet l)ecame seriously ill nine days later. The severity 

 of the infection influences the duration of the period of incu- 

 bation, symptoms setting in later when the infection is not 

 very severe. 



In young pigs the course of the disease is sometimes very 

 acute, animals dropping dead without apparent cause. In other 

 cases the symptoms are depression, staggering gait, and marked 

 dulness. Death may be sudden. 



As a rule the evolution of the disease is more gradual. 

 Dulness, great weakness, inappetence, and thirst ma}?- be ob- 

 served, and in the later stages acute peritonitis with fever, dis- 

 tension of the abdomen and sensitiveness of the abdominal wall. 

 In such cases there is rapid emaciation. Death may occur with- 



