494 BOARD OF AGRICULTURE. [Pub. Doc. 



being kept on the cow all summer. They remained at 

 Jamaica Plain until May 22, when they were sent to 

 Princeton and turned out Avith some of the young cattle 

 used for investigating symptomatic anthrax. From May 4 

 to May 22 two rabbits were given some of the secretion 

 from the actinomycotic quarter of the udder. After the 

 cow was sent away the rabbits were killed and examined by 

 Dr. Frothingham, but no lesions of any sort could be found 

 on autopsy. Before the cow and calf were sent to Prince- 

 ton, some of the actinomyces were 'separated from the milk 

 with a centrifugalizer, mixed with distilled water, and then 

 injected into the thoracic cavity and also into the abdomi- 

 nal cavity of the calf with a hypodermic syringe. The calf 

 ran with the cow all summer in the pasture at Princeton, 

 and thrived magnificently. In the autumn he was as large 

 as a yearling. October 29 the cow and calf were killed at 

 Princeton, and post-mortem examinations were made on 

 both by Dr. Frothingham. The calf proved to be abso- 

 lutely healthy ; not a lesion was found in him anywhere. 

 The cow was healthy with the exception of the udder ; one 

 hind quarter was badly diseased, the other one slightly so. 

 From these experiments it would not appear that there was 

 any danger from the use of milk from cows with actinomy- 

 cosis of the udder. 



Hayes' " Translation of Friedberger and Frohner," page 

 216, says that attempts at transmitting actinomycosis from 

 infected animals, by various European experimenters, to 

 cattle, calves, goats, sheep, pigs, dogs, cats, rabbits and 

 guinea pigs, have proved negative. "It is thought that the 

 ray fungus has a pathogenic effect only in the stage of de- 

 velopment connected with the awns of grain, and that it 

 loses its power of transmission as soon as it has entered the 

 animal body, on account of undergoing some form of in- 

 volution (calcification, etc.). The negative results of the 

 inoculation experiments are of great importance for eluci- 

 dating the question of the transmissibility of actinomycosis 

 from one animal to another, or from one of the lower animals 

 to man. The foregoing considerations tend to prove that 

 infection cannot take place in this manner." 



