No. 4.] VACCINE LYMPH. 475 



The expenditure for equipment would be limited to the 

 purchase of such apparatus as would be required for the im- 

 mediate preparation of the lymph, including fixtures for the 

 stable and offices. The department now has such supple- 

 mentary apparatus as would be necessary, such as micro- 

 scopes, sterilizers, etc. 



Preliminary plans of such a building as has been described 

 have been prepared and are herewith submitted. To meet 

 all requirements of location, etc., some slight modifications 

 might be necessary. It is estimated that this building has 

 sufficient capacity to produce in from four to six weeks all 

 of the vaccine that would be required in the State, even in 

 the event of an extended outbreak of small-pox. An archi- 

 tect's estimate of the cost of the building is |9,000. 



For the investigation of the most modern methods of vac- 

 cine production and for the purchase of apparatus and fur- 

 nishings $2,500 would be necessary. 



An annual appropriation of $3,000 would be required to 

 cover such items of expense as salaries of employees, animals, 

 feed, heat, light and material for the preparation and package 

 of the lymph. 



The location of the college, which is only four hours by 

 train from the extreme ends of the State, would be of distinct 

 advantage in the distribution of vaccine to diflerent points. 

 The town has exceptionally good railroad, express and tele- 

 phone facilities. Fifteen mails arrive and depart each day 

 to and from difterent parts of the State. 



The location in the Connecticut valley, where large herds 

 of cattle are kept and an abundance of hay grown, would be 

 advantageous in procuring animals and feed at a minimum 

 price. 



After careful investigation, this Board considers it feasible 

 to prepare vaccine at the Massachusetts Agricultural College, 

 and believes it can be done there at the minimum of cost. 



