140 GLANDS. 



and free nuclei ; Kolliker mentions also the presence 

 of blood globules, both normal in appearance, and 

 in various stages of alteration. Leydig has described 

 a vascular network which penetrates the interior of 

 the corpuscle, and thus completes its resemblance to 

 a ductless gland ; this author, in fact, does not hesitate 

 to consider the Malpighian corpuscle of the spleen as 

 a minute lymphatic gland. 



spiemc puip. The splenic pulp, the substance of which is tra- 

 versed by the finest vessels, and the most delicate 

 trabeculse, includes elements of different kinds. Its 

 principal bulk consists of cells similar to those of the 

 Malpighian corpuscles (PI. XXII. fig. VII. 1) ; debris 

 of red blood globules, blood pigment, and larger 

 cells with many nuclei, joth of a line in diameter, 

 make up the remainder. In some of these latter 

 elements the formation of red globules seems to take 

 place by endogenous vegetation ; at least this is to be 

 inferred from the drawing by Otto Funke,* in his 

 Atlas of Physiological Chemistry. But Kolliker 

 asserts, on the contrary, that these cells are at first 

 nothing more than aggregations of red globules, 

 around which a membrane has formed, thus consti- 

 tuting a cell, of which these old blood globules 

 become the nuclei, and that they are about to undergo 

 still farther metamorphoses in a retrograde direction, 

 of which he gives drawings confirmatory of his 

 opinion. Are we to conclude then, with Otto Funke, 

 that red globules of the blood are formed in the 



* Formerly Professor of Physiology in the University of Leipzig ; at 

 present occupies the same chair at Freiburg, Grand Duchy of Baden, 

 Germany. (Ed.) 



