148 THE MICROSCOPIST. 



cells of different size and form ; round, oval, and caudate, but 

 no one form predominating over the rest. Some are very large, 

 a, enclosing several minute cells with nuclei. Isolated cells, 

 although in a proportionately small number, contained dark 

 granules, b. For further observations on microscopic patho- 

 logy, the reader is referred to VogeFs Pathological Anatomy, 

 and other similar works. 



The Monthly Journal of Medical Science for May, 1847, 

 contained an account of a new instrument for the diagnosis of 

 tumors. It was presented to the Medical Society of Stras- 

 bourg, by M. Kiin, Professor of Physiology in that city. 



" It consists in an exploring needle, having at its extremity 

 a small depression with cutting edges. On plunging this in- 

 strument into a tumor to any depth, we can extract a minute 

 portion of the tissue of which its various layers are composed. 

 In this manner a microscopic examination of the tumor can 

 be practised on the living subject, and its nature ascertained 

 before having recourse to an operation." 



With respect to the Morphology of various pathological 

 fluids, a great deal has been effected by microscopic investiga- 

 tion. In the Microscopic Journal, vol. ii., is a series of essays 

 on this subject, by Dr. David Gruby, translated from the 

 Latin by S. J. Goodfellow, M.D., which are worthy of careful 

 perusal and experimental verification. The results of Dr. 

 Gruby's researches are appended. 



