372 



EXPERIMENTAL INFECTIONS DURING LIFE 



average temperature of any of the lower animals save 

 the rat and mouse. The accompanying table of nor- 

 mal averages for the animals usually employed in bac- 

 teriological research may be of use in preventing the 

 erroneous assumption that pyrexia is present in an ani- 

 mal, which merely shows its own normal temperature. 



NORMAL AVERAGES. 



B. Special observations comprise some or all of the 

 following, according to the method of inoculation and 

 the character of the virus. 



1. The site of inoculation should be minutely exam- 

 ined at least at weekly intervals, and the neighbouring 

 lymphatic glands palpated. 



2. Any local reaction at the site of inoculation and 

 any other readily accessible lesion should be carefully 

 investigated. Any suppurative process which may 

 occur, whether in the subcutaneous tissues or in 

 joints, should be explored and the pus carefully ex- 

 amined both microscopically and culturally. 



