THE BLOOD AND THE LYMPH. 323 



may be very readily conceived ; and indeed, as I have shown in 

 the Tadpole, may be directly observed. I would, however, 

 remark that I have not unfrequently met with brown, round 

 granule-cells 3 0-004 — 0*005'" in diameter, completely correspond- 

 ing with those mentioned as found in the blood, and which are 

 probably derived from the lymphatic glands. 



From the above facts, it would seem not to admit of doubt 

 that the lymph-corpuscles are formed, like cells, by the develop- 

 ment of membranes around free nuclei, a process which is 

 effected, in the first place, in the commencements of the lym- 

 phatic vessels, but also, and chiefly, in the vasa efferentia of the 

 lymphatic glands. To this is superadded the multiplication of 

 cells by division, which does not always take place. The total 

 quantity of the corpuscles contained in the lymph, compared 

 with that of the blood-corpuscles, is very inconsiderable, not 

 only in the middle-sized and smaller trunks especially, of the 

 lymphatics, but even in the thoracic duct itself is very far from 

 being in an equal proportion; and even there all the elements of 

 the fluid may readily be perceived, without any dilution. More 

 precise enumerations have not yet been instituted, and it can 

 only be added that considerable diversities exist, and that a 

 milk-white chyle is not always also rich in corpuscles. 1 



'[Professor Kolliker appears not to be thoroughly acquainted with the very 

 accurate and extensive researches of Mr. Wharton Jones, embodied in his memoir on 

 1 The Blood-corpuscle, considered in its different phases of development in the Animal 

 Series,' 'Philosophical Transactions/ 1846 ; the publication of which will, we believe, 

 be considered hereafter to constitute an epoch in our knowledge of the blood. It is 

 shown in this Memoir that " the lymph-corpuscle of the Vertebrata is identical with 

 the corpuscle of their blood. In the oviparous Vertebrata it occurs, like the corpuscle of 

 their blood, in the two phases of granule-cell and nucleated cell ; whilst in Man and 

 the Mammifera it occurs like the corpuscle of their blood in the three phases, of 

 granule-cell, nucleated cell, and free celkeform nucleus. 



"The only difference that exists between the corpuscle of the lymph and the cor- 

 puscle in the blood is, as regards the oviparous Vertebrata, the little degree of 

 coloration which the coloured stage of the nucleated cell as yet presents, and, as 

 regards the Mammifera, the small degree of coloration which the coloured stage of 

 free cellaeform nucleus has yet attained," (p. 82). 



Mr. Wharton Jones first pointed out in this Memoir the true nature'of the process 

 which is described and figured in the text as the " bursting," &c, of the lymph-cor- 

 puscles. These changes of form, in fact, are not in general produced by any such 

 cause, but they arise from the amoeba-like motions of the corpuscles, observed 

 by Mr. Jones in the Skate, Frog, and many Invertebrata, and which may be readily 

 enough seen on a smaller scale in the colourless corpuscle of the human blood. 



