THE BLOOD AND THE LYMPH. 329 



corpuscles are derived from the chyle ; and may, consequently, 

 be termed the chyle- or lymph-corpuscles of the blood. Some 

 of them are uninuclear, and correspond in all respects with the 

 small cellular elements of the chyle (vid. § 221) ; some 

 multinuclear, having an average size of 

 0-005'", in which case they so closely re- Fl &- 292 - 



semble pus-corpuscles, that it is quite im- */#& /J\ ffi% 



possible, to distinguish the one from the ^a ^^ ^Br 

 other. The larger corpuscles are rarely as ^ a 'fl^ 

 grauular as the smaller, usually tolerably ™ W ^^ 

 homogeneous, often with clear contents, so 

 that their two or three, rounded, minute nuclei are at once ap- 

 parent. 1 Should this not be the case, acetic acid or water brings 



Fig. 292. Colourless blood-corpuscles, or lymph-corpuscles of the blood : a, b, 

 smaller cells, such as are found in the thoracic duct, viewed on the side (a), and on 

 the edge (b) ; c, c, the same with visible nucleus; d, d, larger cells with nuclei mul- 

 tiple ab origine ; e, e, e, the same after having been acted upon by acetic acid, the 

 nuclei disintegrated or becoming so. 



1 [With regard to the appearances presented by the " nucleus" of the colourless cor- 

 puscle, Mr. Wharton Jones, (1. c. p. 67 for the Frog, p. 72 for Man, the Horse, and 

 the Elephant) shows very clearly that the singleness or multiplicity of this body 

 depends entirely upon the strength of the acetic acid used to bring it out, and we can 

 fully confirm his statement so far as our own observations have gone. If the blood 

 of Man, in fact, be diluted first with water, and then only very dilute acetic acid be 

 added, the " nuclei" of the colourless corpuscles will all, or almost all, be circular, with 

 even edges. If, on the other hand, strong acetic acid be added at once, every variety 

 of form, from mere notching, to apparent division into two, three, or four smaller 

 ones, will be found. " I am satisfied, however, that this is, in both cases, (granule- 

 cell and nucleated cell) merely an appearance produced by the shrivelling together 

 of the walls of the single cellaeform nucleus, in consequence of the action of the 

 acetic acid. 



" It is proper to observe, that I have come to this conclusion, only after having par- 

 ticularly tested the point by repeated, careful, prolonged, and varied observations. 

 Nor is the determination of the point of small moment, as on the appearance of a 

 multiple nucleus, which I have thus shown to be artificially produced, and on a similar, 

 but I believe equally artificially produced appearance of a multiple nucleus in the pus- 

 corpuscle, a particular view has been founded as to the first formation of the nucleus, 

 and, indeed, as to cell-development generally." (Wharton Jones, 1. c, pp 67-8.) 



It will be observed that in the text Professor Kblliker admits that the multiple 

 " nuclei" may be still further broken up by the action of reagents. 



The existence of any difference of specific gravity between the colourless and the 

 red corpuscles of the blood may be doubted ; their relative positions in masses of 

 blood, to which reference is made above, being fully accounted for by the aggregation 

 of the red corpuscles into rolls. 



With regard to the blood-corpuscles of the Invertebrata, Mr. Wharton Jones's 



