114 



THE VASCULAR SYSTEM 



limb being higher and its hue redder, owing doubtless to the fact 

 that the vaso-motor nerves were cut. The venous circulation 

 was observed to be good immediately after the operation." The 

 collodion dressing, however, contracted and impeded the circula- 

 tion in the limb which became swollen, so that after fifty hours 

 the animal was killed. 1 The most striking of these remarkable 

 experiments is that of transplanting the kidneys from one cat 

 to another. Secretion of urine may begin immediately after the 

 arterial circulation is re-established. In the best cases the func- 



FIG. 3. The graft ready for insertion. 



FIG. 4. The operation completed. 



tion of the kidney was for some twenty days almost normal. 

 120 to 160 c.c. of urine a day were secreted, and urea in proportion 

 to the proteid eaten. When feil on raw meat 2*7 to 5*1 grms. of 

 urea were passed per diem. The N cats were fat and in good health, 

 with glossy skin and good appetites, playing, running, and jumping 

 about the room. Nevertheless there was some albumen in the 

 urine, and oedema of the kidneys leading to their slow and pro- 

 gressive enlargement. Upon the twenty-ninth day one cat was 

 well, and then gastro-intestinal symptoms set in and the animal 

 died on the thirty-first day. 



1 Guthrie reports " a transplanted fore-limb without any serious derangement of 

 metabolism, six days after the operation." (Jmirn. Amtr. Med. Assoc.,1908, li. p.1658.) 



