348 RESEARCHES ON CORTICAL LOCALISATION AND 



the most elaborately detailed investigations, even when repeatedly 

 confirmed, may still fail to gain general acceptance. 



The last investigation which will be referred to is not of direct 

 physiological interest, but is nevertheless worthy of mention owing 

 to its bearing on the subject of heredity. J. P. Karplus has recently 

 published a work which deals with the fissuration of the human cere- 

 brum from the aspect of family likeness. He has examined in a series 

 of cases the cerebra of two or more members of a family, and also the 

 brains of several members of families in the ape, dog, rat, and goat. 



He draws interesting conclusions with regard to the family likeness 

 of the pattern of the fissures. He further finds that, whilst in the 

 monkey the two hemispheres resemble one another, in man the original 

 bilateral symmetry of fissuration is lost, and the sulci of the individual 

 hemispheres possess a family permanence. 



Whilst it is true that the convolutional pattern of the brain does 

 not run hand in hand with, and in fact bears little relationship to, 

 the various histologically differentiated areas into which the cerebral 

 cortex has been divided, the truth that the former is susceptible to 

 the impress of heredity is at least suggestive with regard to the possi- 

 bility of this in the case of the latter. 



BIBLIOGRAPHY 



L. Bianclii, On the Teaching of Flechsig with regard to the Perceptive 

 and the Associative Zones. Internat. Med. Congress of Madrid, 1903. Text- 

 book of Psychiatry, translated by J. H. Macdonald, 1906. 



J. S. Bolton, The exact Histological Localisation of the Visual Area of 

 the Human Cerebral Cortex. Phil. Trans., vol. 193, 1900. The Histological 

 Basis of Amentia and Dementia. Archives of Neurol., vol. ii., 1903. The 

 Functions of the Frontal Lobes. Brain, 1903. Amentia and Dementia : a 

 Clinico-Pathological Study. Journ. Ment. Sci., 1905-8, chiefly April 1905, 

 April 1906, and April and' July 1908. 



K. Brodmann, Beitrage zur histologischen Lokalisation der Grosshirnrinde. 

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A. W. Campbell, Histological Studies on the Localisation of Cerebral 

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