84 ENDOCRINE GLANDS 



dangerous consequences. It causes abortion, hemorrhages 

 and even cardio pulmonary complications which resemble 

 the severe gravid cardiac accidents. 



4. ABORTIVE TYPE. Charcot and his pupils, Pierre 

 Marie among these, have shown that next to the typical 

 types of these affections mild or abortive cases exist. 



According to P. Marie, the fundamental symptom of 

 Basedow's disease is tachycardia, and goitre, exoph- 

 thalmos and tremor may be missing. 



The abortive cases are characterized by tachycardia, 

 either with exophthalmos without a goitre, or with a 

 goitre and no exophthalmos, or finally alone. The vaso 

 motor, nervous, psychic changes which accompany these 

 mild cases are sufficient to relate it to exophthalmic 

 goitre. Next to these mild cases, we must place various 

 cardiac neurosis. In certain defectives, having no signs 

 of Basedow's disease, not even a goitre, fatigue or excite- 

 ment cause palpitations and tachycardia, a cardio vascular 

 and nervous instability and even a slight tremor. Certain 

 cases of tachycardia, not well classified, occurring inter- 

 mittently and in paroxysms, which we saw during the 

 war were probably due to disturbances in the thyroid 

 function. These cardiac neuroses are closely allied to 

 attenuated cases of Basedow's disease and there is no def- 

 inite line of demarcation between them. 



5. ASSOCIATED FORMS. Basedow's disease is liable to 

 co-exist with different nervous affections of the nervous 

 system: syringomyelia, epilepsy, general paresis and 

 particularly tabes. In the latter case it is probably of 

 luetic origin. 



Combinations with other glandular syndromes are very 

 curious: acromegalia, gigantism, Addison's disease, myx- 

 edema, etc. The latter follows the goitre in certain cases fol- 

 lowing radiotherapy or the two affections evolute together. 



