100 ENDOCRINE GLANDS 



increased and is particularly abundant around the blood 

 vessels and penetrates into the gland in various directions, 

 giving it a lobulated appearance resembling the thyroid 

 of a child. The vesicle presents a variety of changes : in 

 certain places the colloid is decreased, in others there 

 seems to be hyperplasia of the cells. Endo and periar- 

 teritis is the rule, but there are no follicular lesions. 

 Tubercle bacilli are not found; inoculation is negative. 

 This thyroid sclerosis takes on the appearance of an ordi- 

 nary inflammation. 



Clinically sclerous tuberculosis of the thyroid gives the 

 symptoms of a latent atrophic sclerosis. In very rare 

 cases it may become hypertrophic and give rise to a hard 

 tumor, developing rapidly and causing pain and respira- 

 tory Disturbances. This is the so-called canceriform 

 thyroiditis which simulates cancer. It may also cause 

 a dysthyroiditis giving rise to abortive or typical symp- 

 toms of Basedow's disease. Laignel-Lavastine, Mantoux 

 and Ramond have reported similar findings. The de- 

 velopment of exophthalmic goitre on top of a tuberculosis 

 of the gland are to-day well known. To the period of 

 hyperthyroidism succeeds a period of hypothyroidism 

 resulting in myxedema. 



* * 



SYPHILIS OF THE THYROID is more common than 

 is suspected. 



In children, hereditary syphilitic sclerosis is possible in 

 a certain number of cases of myxedema, and specific treat- 

 ment is indicated in these cases as well as organo therapy. 



Acquired syphilis is better known. During the second- 

 ary stage can be observed temporary congestions of the 

 thyroid. Tertiary thyroiditis or gumma of the thyroid 





