142 ENDOCRINE GLANDS 



infectious disease a bad outlook. It can, however, be 

 considerably improved or even cured by organo therapy. 



Adrenal organo therapy can be administered in three 

 different ways: 



(a) The fresh gland, preferably that of a calf, is chopped 

 up in doses of 2 to 5 grams. It is generally not well tolerated. 



(6) Suprarenal powder of the total extract of the desic- 

 cated gland. 



(c) Suprarenalin. 



INDICATIONS. From a physiological point of view, we 

 are led to believe that the total extracts are indicated in 

 the cases in which toxic symptoms predominate, while 

 suprarenalin which keeps up the vascular tonus, and 

 the arterial pressure, is indicated in those cases in which the 

 cardio vascular disturbances are the most marked. As a 

 matter of fact, suprarenalin is advisable in all cases. It 

 has the advantage of being easily manipulated. The 

 extracts of the adrenals have a variable activity; they can 

 however give better results when the asthenia, and the 

 gastric and nervous disturbances are particularly marked. 



METHOD OF ADMINISTRATION. The best preparation 

 to use is a solution of 1 to 1000 of epinephrin. The 

 method of administration is to be taken into consideration, 

 for suprarenalin is very toxic when injected intravenously; 

 it is much less so subcutaneously and practically harmless 

 when given by the gastro intestinal tract. 



1. By mouth, suprarenalin gives very good results, 

 particularly in the cases of cardio vascular asthenia during 

 infectious diseases, providing it is given in sufficiently 

 large doses: 20 to 100 drops of a solution of 1 to 1000 

 daily. Whatever the daily doses, it must be given 

 fractionally during the day, because of the ephemeral 

 action of suprarenalin. This type of medication can be 

 administered without any bad effects for several weeks. 



