230 ENDOCRINE GLANDS 



(6) To the nervous disturbances occurring in the ovarian 

 insufficiency are associated certain genital psychoses, 

 observed very commonly, however, at puberty, or at the 

 time of the menses. The psychoses of puberty manifest 

 themselves in most cases by mental confusion; less 

 commonly by acute mania or melancholia. 



The mental psychoses appear a few days before the 

 menses and only disappear after they are over. The 

 usual type is erotism or mysticism.' 9 



The ovarian origin of these cerebral disturbances is 

 proved by the fact that they coincide with other symp- 

 toms of ovarian insufficiency and that they are improved 

 by ovarian organo therapy. 



3. OBESITY. This may be observed at various stages 

 of the genital life of women and sometimes may be due to 

 ovarian insufficiency (Carnot). 



Post nuptial obesity, which comes on a few months 

 following marriage, is probably due to the glandular 

 changes brought about by sexual activity. 



Gravid obesity is very frequent. Many women grow 

 fat at the beginning of pregnancy. The adiposity can 

 persist after delivery in women who previously were thin. 



VI. THYROID-OVARIAN INSUFFICIENCY. 



Any disturbance of the thyroid functions in infancy or 

 adolescence may affect the genital system. The hypo- 

 function of the ovary is then secondary to a hypothyroid- 

 ism. In these patients are found associated symptoms 

 of both thyroid and ovarian insufficiency. 



They are small women, showing a delayed physical 

 development, pilary disturbances and lowering of the body 

 temperature. They are apathetic, subject to headaches, 

 etc., and puberty is delayed. The uterus stays infantile. 



* Here again the pituitary must not be considered blameless. 



