236 ENDOCRINE GLANDS 



This gives rise to a quantity of abnormal hormones, which 

 causes the hemorrhages and modifies menstruation. 



It is still hard to say why this only occurs at puberty or 

 at the menopause. 



TREATMENT. 



Hyperf unction of the ovary can be treated : 



(a) HYGIENE. This consists in preventing the pelvic 

 congestion, by a careful diet, eliminating all stimulating 

 foods or drinks and avoiding constipation. 



(b) MEDICATIONS. The usual hemostatics, ergot, 

 calcium chloride, hamamelis, hydrastis are usually 

 unsuccessful. Very hot vaginal irrigations or ice on the 

 hypogastrium may be beneficial. 



The injection of blood serums (pure serum, antitoxin, 

 etc.) subcutaneously in doses of 20 to 30 centigrams 

 are often efficacious. Unfortunately, their action is 

 only temporary. 



(c) ORGANO THERAPY. Ovarian extract is contra- 

 indicated. Thyroid, pituitary and mammary organo 

 therapy have a definite anti hemorrhagic effect. Clinical 

 observation has shown that thyroid extract in small doses 

 0.005 to 0.01 centigrams daily) seem to regulate the 

 thyroid functions and cause a cessation of the geni- 

 tal hemorrhages, 



Dalche advises the use of pituitary extract which has an 

 inhibitive action on the ovary and which, furthermore, 

 increases the coagubility of the blood and causes a con- 

 traction of the uterus and its blood vessels. 



Mammary extract is very advisable by reason of its 

 functional antagonism between the breast and the ovary 

 (Bell, Crouze, Batuaud, Pochon). 



During the hemorrhages, it can bq. administered in doses 



