THE SYMPATHETIC SYSTEM 245 



have been previously mentioned. We will simply recall 

 a few: 



1. PLURIGLANDULAR SYNDROMES WITH THYROID PRE- 

 DOMINANCE. Basedow's disease with ovarian insuffi- 

 ciency and amenorrhea. 



Myxedema with testicular atrophy. 



Myxedema with mammary hypertrophy. 



2. PLURIGLANDULAR SYNDROMES WITH PITUITARY 

 PREDOMINANCE. Gigantism with infantilism. Acrom- 

 egalia associated with glandular insufficiency (amenorrhea) 

 or with symptoms of hyperf unction of the adrenals: 

 arterial hypertension, and Atheroma (Claude) or hyper- 

 plasia of the thyroid and adrenals. (G. Ballet and 

 L. Lavastine). 



3. PLURIGLANDULAR SYNDROMES WITH OVARIAN 

 PREDOMINANCE. The most important are the thyroid 

 ovarian syndromes: 



Hypertrophy of the thyroid at puberty or dur- 

 ing pregnancy. 



Thyroid reaction associated with ovarian insufficiency. 

 These symptoms resemble Basedow's disease. In some 

 cases it may give all the symptoms of a true Base- 

 dow's disease. 



SECOND GROUP. 



This is characterized by the association of two uni- 

 glandular syndromes, each of which having its pecul- 

 iar characteristics. 



This is the case: 



Exophthalmic goitre, associated with Addison's disease. 



Exophthalmic goitre, associated with acromegalia 

 (Murray) or with gigantism (G. Ballet). 



Myxedema, following Basedow's disease. 



Myxedema, associated with acromegalia (Burchard). 



