ORGANO THERAPY. 



PHARMACOLOGICAL FACTS. 

 BY H. CARRION. 



Former Chief of Laboratory of "T Assistance Publique" at the Saint-Antoine Hospital. 



We include under this all animal products utilized as 

 medications, be they furnished by a gland of internal 

 secretion like the thyroid, or a gland of external secretion 

 like the pancreas, or obtained from a non-glandular sub- 

 stance like muscle extract. 



As a general rule, we employ the organs of healthy and 

 normal animals. In certain cases, however, we utilize 

 animals which have been intentionally modified physio- 

 logically. For instance, Ballet and Enriquez have utilized 

 for the treatment of hyperthyroidism, the blood of animals 

 deprived of their thyroid for a certain time by means of a 

 surgical interference. Carnot and Deflandre have con- 

 ferred hemopoitic properties on the serum of certain 

 animals by means of repeated withdrawals of blood and 

 have utilized it in the treatment of anemias. 



In reality, all serums employed in therapeutics could be 

 considered as a separate subject and included under the 

 title of "serotherapy." 



PHYSIOLOGICAL BASIS OF ORGANO THERAPY. 



Certain general considerations are the basis of organo 

 therapy and it is well to keep these in mind. 



One of the most important facts to remember is the 

 specificity of organs, not only from a functional and ana- 

 tomical point of view, but also chemically. Each organ 

 is made up of certain definite substances which are partic- 

 ular to it. 



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