362 ENDOCRINE GLANDS 



to give to the organism the secretions which it is missing 

 and partly to stimulate the function of the deficient organ. 



Glandular synergy by means of which certain organs 

 supplement each other, allows us sometimes to substi- 

 tute the extract of one organ for another. Just as we 

 know that the ingestion of an extract is susceptible to 

 stimulate the function of an organ other than the one 

 it has been extracted from. These facts are well worth 

 remembering when it comes to understand certain indi- 

 cations or explain certain effects. 



As regards certain particular qualities which are utilized 

 in the treatment of certain symptoms without any patho- 

 logical relation to the organ from which the extract is 

 obtained, (suprarenalin to contract the blood-vessels, for 

 instance) there is no general rule for these. 



CONTRAINDICATION TO ORGANO THERAPY. 



There does not seem to be any general contraindication 

 to the use of the organo therapy and it does not prevent 

 the use of any other therapeutic method. 



This results in organo therapy being very convenient to 

 employ and, furthermore, it is nearly always without 

 danger and this is easy to understand wiien we remember 

 that nothing foreign is introduced into the organism. 



The danger of possible anaphylaxis has been mentioned 

 by some. It seems that this theory has been abused of, 

 and when this phenomenon is suggested as occurring after 

 the oral administration of extracts of organs it seems to be 

 going too far. 



There are, however, a certain number of facts which we 

 must keep in mind when we administer this type of 

 medication. The first one is that a few of these products 

 have a fairly high toxicity. Carnot drew attention to the 

 toxicity of bile which cannot be administered without a 



