loo ENDOCRINE THERAPEUTICS 



which Carnrick introduced some years ago depend 

 much on this for their tonic effect, especially in 

 the low blood-pressure cases of neurasthenia, 

 which are the more common : in high- pressure 

 cases, on the contrary, they often seem to 

 raise pressure above the safety point and above 

 the point of brain comfort. Sajous further 

 says, " The pituitary is now granted four in- 

 ternal secretions : one each for the anterior 

 and posterior lobe, one for the infundibulum, 

 and one for the organ as a whole." As shown 

 by Renon, " pituitary extract raises the depressed 

 arterial tension and corrects purely functional 

 disorders of rhythm. It is recommended in 

 doses of 3 to 6 grains of the whole gland in 

 myocardial weakness, particularly hi that which 

 is due to infections when the blood-pressure is 

 receding, the pulse is becoming more rapid, and 

 the urine scanty. While less active than digi- 

 talis as a diuretic, it nevertheless serves a 

 valuable purpose in this connexion. 



" It is contra- indicated in aortic affections, in 

 any disorder in which high vascular tension pre- 

 vails, and where there is any tendency to anguinal 

 pains, which it tends greatly to aggravate." 



In England we have not as yet made the use 

 of these powerful aids to failing circulation and 



