ANTERIOR PITUITARY GLAND 109 



After 55 or 60, when we often see endocrine 

 deficiencies producing premature senility, pit- 

 glandin failure forms a very important part of 

 the complex ; it is generally associated with 

 thyroid failure. The symptoms are the well- 

 known ones generally classed under subthyroidism. 

 These are, raised blood- pressure with its usual 

 signs of cardiac strain and fatigue, shortness 

 of breath, and easily produced muscular fatigue. 

 If the cerebral arteries are affected, there may be 

 vertigo and tinnitus. In short, there are the 

 symptoms of early arterio-sclerosis : premature 

 sexual and vesical weakness, which so often occur, 

 point to pitglandin deficiency. In practice it 

 is found that hormotone treatment by combina- 

 tions of the thyroid and pitglandin are most 

 effective. 



Pituitrin should be avoided, for it tends to 

 raise pressure. The pitglandin balances effec- 

 tually the depressing effects of the thyroid, but it 

 should be given in full doses, 2-6 grains of dried 

 extract daily. My experience shows that it 

 restores sexual and vesical power and generally 

 raises the tone and capacity of the whole system. 

 It does not raise blood-pressure, but, I believe, 

 helps to lower it. As in early life it promotes 

 gonad activity, so in later life it reawakens those 



