OVARIAN THERAPY 159 



cessful cases are those in which menstruation is scanty. Certainly there 

 would seem to be good reason for organotherapy in those cases of sterility 

 associated with congenital hypoplasia of the uterus, and often accom- 

 panied by dysmenorrhea, or amenorrhea. Here the ovarian extract is 

 best combined with extract of anterior pituitary lobe. Rational though 

 such medication may be, the clinical results are rarely striking and often 

 quite negligible. 



What has been said concerning the treatment of sterility would apply 

 with equal force to the treatment of dysmenorrhea. It need scarcely be 

 said that secondary dysmenorrhea, i. e., the form due to the presence of 

 definite pathologic conditions in the pelvis (inflammatory disease, neo- 

 plasm, displacements, etc.), offers no field for the use of ovarian therapy. 

 In primary dysmenorrhea, however, we have to deal with a developmental 

 defect a uterine hypoplasia which is assuredly of endocrine origin. 

 Dysmenorrhea and sterility a/e commonly associated in this condition. 

 The indication for organotherapy is a real one. Extracts of the entire 

 ovary are here indicated, in combination with anterior pituitary substance 

 and often with thyroid. 



