874 



HAEVEY G. BECK 



an increased density of bone in the roof of the orbits and sphenoidal and 

 ethmoidal sinuses was also noticed in a large proportion of these cases. 

 Other cranial bone lesions have been associated with hypopituitarism, 

 such as hydrocephalus, fracture, syphilitic ostitis, Paget's disease, etc. 

 The effect of these in producing hypopituitarism is probably that of in- 

 creasing intracranial tension causing pressure, atrophy and hypofunction 

 of the gland. 



The character of the sella turcica in its relation to salient features of 

 symptomatology is embraced in the following tabulation by Timme(fe). 



Character of Sella Turcica Salient Features of Symptomatology 



Group "A"- With no demonstrable 

 physical enlargement or diminu- 

 tion. 

 Seemingly normal sella. 



Group "B" With demonstrable 

 smallness of sella turcica and lack 

 of cavity space for proper expan- 

 sion of the gland. 



Under activity. Usually under- 

 sized ; maxillary prognathism ; 

 crowded teeth; adiposity; Froh- 

 lich's dystrophy; low blood pres- 

 sure; menstrual disturbances; di- 

 minished libido; diabetes insipi- 

 dus. Somnolence; mentally dull 

 and apathetic; lack of concentra- 

 tion. High sugar tolerance. 



Overactivity. Frequent and severe 

 headaches ; rapid growth ; moder- 

 ate contraction of visual fields; 

 sexual trends; high blood pres- 

 sure. Great mental activity; in- 

 itiative; irritability. Low sugar 

 tolerance. 



Signs of congenital hypopituitar- 

 ism ; with or without head- 

 aches ; Fro'hlich's dystrophia adi- 

 posogenitalis ; lack of proportion- 

 ate skeletal build; f atigability ; 

 adiposity ; usually small genitalia 

 and perhaps reversion in type; 

 sex abnormalities. 



Mental Signs. Compulsions; lack 

 of inhibition; pathological liars; 

 intellectual and moral inferior- 

 ity ; little initiative ; epilepsy. 

 High sugar tolerance. Frequent 

 relative lymphocytosis. 



