DYSTROPHIA ADIPOSOGENITALIS 



913 



24L.24. 



In my personal observation of a series of forty-six cases treated with 

 gland substance twenty-six showed definite improvement, nine marked 

 improvement, and eleven remained unimproved ; in three of these eleven 

 treatment was not continued long enough to determine its efficiency. Suffi- 

 cient time has not elapsed to say whether the results in those benefited 

 are permanent, although a number of these patients have had no treatment 

 for three or four years, and have remained free from symptoms. 



Organotherapy has a remarkable 

 effect in redistributing the fat in 

 dystrophia adiposogenitalis. My at- 

 tention was directed to this phenome- 

 non in 1915, in the case of a woman 

 aged 41 years, married, weighing 125 

 pounds. She presented three fairly 

 well defined symptom -groups, viz. ; 

 those referable to pituitary insuffi- 

 ciency : fat dystrophy and genital hy- 

 poplasia ; those referable to ovarian 

 insufficiency: frigidity, sterility and 

 amenorrhea; those referable to thy- 

 roid insufficiency : mental, neuromus- 

 cular and trophic skin disturbances. 

 The patient was an invalid unable to 

 attend to ordinary household duties 

 on account of apathy, stupor and dull- 

 ness and feeling of intense exhaustion. 



The most conspicuous symptom 

 was obesity of the girdle type. She 

 noticed an enormous increase in the 

 size of her hips, buttocks and waist, 

 and although she had gained about 

 20 pounds in 10 months there was 

 no increase in the rest of her body. 

 On the basis of a pluriglandular 

 syndrome a combination of gland substance derived from the three re- 

 spective glands was administered with striking results both in regard to 

 her general condition and her obesity. The tremendous folds of fat 

 rapidly disappeared in spite of the fact that she practically lost no weight. 

 Frequent alterations of her clothes became necessary, and measurements as 

 recorded by her dressmaker showed waist 30 inches, hips 43 inches be- 

 fore treatment; these decreased after eight weeks of treatment to 26 inches 

 and 36% respectively, and after eleven weeks of treatment to 25 and 

 35% inches. Thus the waist measure decreased 5 inches, and the 

 hips 7% inches while the patient lost only one pound in weight. However, 



27*.. 



17V.. .181 1 



fl 



Fig. 25. Dark, continuous line and 

 outside figures represent the body outline 

 and circumference measurements re- 

 corded before treatment. The dotted 

 lines and inside figures represent the 

 same recorded 8 weeks later. GROUP A, 

 CASE IV. 



