INDEX 



931 



Cretinic degeneration, etiology of, the- 

 ories as to, Plutonian theory of 

 Repin, 453. 



water supply, 451. 



geographical and orographical dis- 

 tribution of, 442. 



historical, 441. 



pathology of, in central nervous sys- 

 tem, 461. 



in other ductless glands, 461. 



in skin, 461. 



in special senses, 462. 



metabolism, 463. 



osseous system, 463. 



sexual retardation, 462. 



thyroid gland, 458. 



atrophic lesions, 461. 



pathogenesis of goiter, 458. 



prevalence of, 443. 



prophylaxis against, 469. 



relation to, of thyroid gland, 449. 

 in pathology, 458. 



in symptomatology, 465. 



in treatment, 471. 



of water supply, 451, 469. 



symptomatology of, anomalies of 

 dentition and jaws, 466. 



appearance, 465. 



clinical, 464. 



deaf -mutism, 467. 



goiter, 465. 



goiter heart, 467. 



hematology of, 468. 



idiocy, 466. 



myxedema, 466. 



nervous system, 466. 



thyroid gland, 465. 



See also Diagnosis, pathology of. 



treatment of, aid of intestinal anti- 

 septics, 472. 



preventive, 469, 470. 



thyroid, 471. 



Cretinism, delayed growth in, 391. 



endemic, distinguished from en- 

 demic goiter, 381. 



experimental feeding on animals, 

 results of, 230. 



history of, 225. 



implantation of thyroid tissue in, 91. 



metabolism in, gaseous, 394. 



osseous system in, 390. 



long bones, 392. 



skull, 392. 



symptomatology of, 399. 



thymus therapy in, 143. 



thyroid therapy of, 88. 



changes wrought by, in atrophied 



thyroid gland, 89. 



Cretinism, thyroid therapy of, changes 



wrought by, mental, 89. 

 physical, 88. 



dosage for, 90, 91. 



Cretins, "typical" of Simpson, 229. 

 Crile's kinetic theory of exophthalmic 



goiter, 313. 

 "Cryptorrhetic," 5. 

 Crystalline lens, in tetany, 614. 

 Gushing, Harvey, experiments of, on 



removal of pituitary body, 65. 



on perverted function of pituitary 

 gland, of dyspituitarism (1910), 66. 



Cutaneous appendages, in hypothy- 



roidism, 407. 

 Cutaneous symptoms, of autonomic 



origin, 329. 



canities, 331. 



edema, 330. 



nails, 331. 



pigmentation, 330. 



purpura, 330. 



scleroderma, 330. 



various, 331. 



Vigoroux's sign, 329. 



of hypothyroidism, 405. 



of tetany, 623. 



Cysts, of hypophysis cerebri, 802. 



parathyroid, 572. 



thyroid, 293, 294. 



Cytolysis, specific, as method of creat- 

 ing gland deficiency, 41. 



Dalrymple's sign, 319. 



Dandy, W. E., experimental extirpa- 

 tions of, of pineal gland (1915), 68. 



Darwin, idea of, on pangenesis, 62. 



Deaf-mutism, in cretinic degeneration, 

 462, 467. 



Deafness, in cretinic degeneration, 462. 



thyroid treatment of, 102. 

 Degeneration of the thyroid gland, 



284. 



amyloid, parenchymatous, fatty, etc., 

 284, 285. 



calcareous, 285. 



hyaline, 284. 



Degenerative changes, in hypophysis, 

 due to infectious diseases, 779. 



Dementia precox, thymus therapy for, 

 144. 



thyroid therapy in, 101. 

 Dentition, anomalies of, in cretinic de- 

 generation, 466. 



in hypothyroidism, 409. 



See also Teeth. 

 Dermatopathies erythema, in Graves 



disease, 331. 



