INDEX 



951 



Immunotherapy, hormonal, 82. 



Implantation of thyroid tissue, in cre- 

 tinism and myxedema, 91. 



Impotence, in hypothyroidism, 416. 



pituitary (anterior) therapy in, 121. 



Inanition, effect of, on structure of 

 thyroid epithelium, 221. 



Infantile arthritism of Comby, 55. 



Infantilism, in dystrophia adiposogeni- 

 talis, 876. 



Infarction, of hypophysis cerebri, 773. 



as method of depression of hor- 

 mones, 41. 



Infected wounds, hypophyseal hormono- 

 therapy for, 115. 



Infections, causing dystrophia adiposo- 

 genitalis, 905. 



leading to exophthalmic goiter, gen- 

 eral, 307. 



iodin and thyroid extract, 309. 



nasal disease, 308. 



pregnancy and lactation, 308. 



syphilis, 308. 



tuberculosis, 308. 



tetany in, prognosis of, 670. 

 Infectious diseases, changes in hy- 

 pophysis cerebri due to, 779. 



circulatory failure of, suprarenal 

 therapy for, 132. 



collapse of, suprarenal therapy for, 

 133. 



tetany associated with, 649. 



thyroid treatment in, 103. 

 Infectious origin, of hypothyroidism, 



384. 

 Infectious theory of exophthalmic 



goiter, 309. 

 Injections into gland, in treatment of 



exophthalmic goiter, 372. 

 Innervation, of hypophysis cerebri, 



708. 



of the parathyroids, 502. 



of thyroid gland, 208. 



Inosinic acid, as toxic agent in intoxi- 

 cation theory of parathyroid tetany, 

 549. 



Inosmic acid, in tetany, 635. 



Insanity, occurring in exophthalmic 

 goiter, 347. 



relation of thyroid gland to, 411. 

 Insomnia, in exophthalmic goiter, 346. 

 Insuffisance pluriglandulaire, 903. 

 Internal secretions, action of, on cen- 

 tral nervous system, 76. 



classification of, as autocoids, 4. 



as erregende and hemmende, 5. 

 hypertensive and hypotensive, 5. 



conditions determining, 10. 



Internal secretions, conditions deter- 

 mining, chemical, 11. 



demonstration of presence of ac- 

 tive principles, 11. 



histological, 10. 



physiological, 11. 



history of, accepted view of, enunci- 

 ated by Johannes Miiller, 57. 



acromegaly or gigantism, 55, 56. 



action of, on central nervous sys- 

 tem, 76. 



Addison's disease, 55. 



Addison's monograph "On the 



Constitutional and Local Effects of 

 Diseases of the Suprarenal Cap- 

 sules," 54. 



antispasmodics, 49. 



-Brown-Sequard in 1891, 62. 



carbohydrate metabolism, 63. 



correlation with the sexual func- 

 tion, 69. 



discovery of Claude Bernard 



(1849), that temporary glycosuria or 

 medullary diabetes mellitus may be 

 produced by puncture in region of 

 fourth ventricle of the brain in the 

 dog, 59. 



glycogenic function of liver, 

 Claude Bernard (1843), 58, 59. 



iodothyrin in body, suggesting 



relation of thyroid gland to iodin 

 metabolism, 63. 



pancreas possesses an internal 

 secretion as well as a digestive func- 

 tion, 63. 



parathyroids and calcium 

 metabolism, Ivar Sandstrom (1880), 

 63. 



"dystrophia adiposogenitalis" of 

 Frb'hlich, or pituitary obesity, 53. 



exophthalmic goiter, 51. 



experiment of A. A. Berthold 

 (1849), in transplanting testes of 

 fowl to another part of its body, 

 57. 



-Brown-Sequard (1856), in pro- 

 ducing Addison's disease by removal 

 of suprarenal capsules, 60. 



-Brown-Sequard (1889), on re- 

 juvenation by administration of tes- 

 ticular extracts, 62. 



-E. Frank (1912), and Harvey 

 Gushing (1913), that there is a poly- 

 dipsia and polyuria deriving from the 

 pituitary body, 59. 



Mering, von, Joseph (1886), 



producing experimental diabetes by 

 ingestion of phlorizin, 63. 



