INDEX 



Intestine, effects of posterior lobe feed- 

 ing of hypophysis on, 755. 



Intoxication theory of parathyroid 

 tetany, toxic agent, ammonia as, 542. 



guanidin and methylguanidin as, 

 544. 



histamin as, 544. 

 -inosinic acid, 549. 



thymus secretion, 549. 



xanthin as, 544. 

 Intoxications, chronic, as factors in 



hypothyroidism, 385. 



in parathyroid glands, 564. 

 tetany associated with, 650. 



prognosis of, 670. 

 Intrapulmonary injections of gland ex- 

 tracts, 35. 



Intrathoracic struma, 318. 



Intravenous coagulation, due to sub- 

 stances in unboiled tissue extracts, 

 30. 



Intravenous injections, errors and ad- 

 vantages of, 32. 



given apparently specific reaction ob- 

 tained from extracts of several dif- 

 ferent glands, 30. 



gland extract as heterogeneous mix- 

 ture of many substances, 29. 



immunity developed, 31. 



intravenous coagulation induced by 

 substances in unboiled tissue ex- 

 tracts, 30. 



nonspecific substances in tissue ex- 

 tract, cholin, 29. 



histamin, 29. 



nucleo-proteins, 29. 



of suprarenal extracts, Oliver and 

 S chafer's experiment on effects of, 

 28. 



postulates to prove hormone con- 

 tent in given organ extract, 28. 



quantitative aspects of, 31. 



sources of error in experiments on, 

 Biedl on, 28. 



Gley on, 28. 



Lewandowsky on, 28. 



toxic material due to process of dis- 

 integration of protein substances, 

 29. 



1 anaphylactic shock as factor in, 



29. 



boiling as means of eliminating, 



30. 



tryptic enzymes of blood in for- 

 mation of, 29. 



variation in abnormal products of 

 extract, even in same gland, 32. 



"lod-Basedow" complex of Kocher, 

 301. 



lodid, experimental feeding with, 233- 



^JoO. 



lodin, compounds of, in other tissues 

 than thyroid, 252. 



- in thyroid gland, iodothyroglobu- 

 lin, 253, 261. 



internal secretion, evidence 



connecting, 259. 



"thyreoantitoxin," S. Frankl's, 

 253. 



-"thyroidin" (iodothyrin), Bau- 

 mann's, 253, 260. 



- "thyroprotein," Notkin's, 253. 



thyroxin, 254, 261. 



lodin, content of, in thyroid gland, 84, 



248. 

 age, 250. 



diet, 251. 



distribution of, 252. 



relationship between thyroid 

 activity and, 262. 



seasonal variations, 250. 



sex, 250. 



-table of, 249. 



therapeutic efficiency of thy- 

 roid preparations running parallel to, 

 85. 



distribution of, in organisms, 247. 



Hunter's and Kendall's method for 

 detecting presence of, 246. 



in parathyroids, 551. 



producing exophthalmic goiter, 309. 

 - relation of, to developmental proc- 

 esses, 187. 



therapeutic test with, and with thy- 

 roid extract, for hyperthyroidism, 

 498. 



thyroid gland, 232, 244. 



content of, 84, 248. 

 distribution of, 252. 



use of, in treatment of exophthalmic 

 goiter, history of, 52. 



lodin administration, atrophy of the 

 thyroid gland following, 283. 



lodin metabolism, relation of thyroid 

 gland to, suggested by discovery of 

 iodothyrin in body, 63. 



lodin-thyroidism, 301. 



Iodothyrin, 253. 



discovery of, in body, suggesting 

 relation of thyroid gland to iodin 

 metabolism, 63. 



evidence for and against its being 

 the internal secretion of the thyroid, 

 260. 



