954 



INDEX 



lodothyrolobulin, connection of, with 

 internal secretion of gland, 261. 



digests of, 254. 



elementary j composition of, from 

 different sources, 254. 



molecular weight of, 253. 



percentage of weight of the dried 

 gland, 254. 



-solubility of, 253. 



variability of iodin, percentage of, 

 254. 



Islands of Langerhans, as source of 

 pancreatic glycosuria, 63. 



Jellinek's sign, 324. 



Joffroy's sign, 320. 



Joints, condition of, in tetany, 623. 



Katatonia, differentiated from tetany, 

 677. 



Kendall, isolation by, from thyroid of 

 crystalline substance named thyro- 

 oxy-indol or thyroxin (1915), 84. 



analyzed and prepared (1918), 84. 

 Kidneys, action of epiiiephrin on, phar- 



macodynamic, 127. 



effects on, of hypophysis feeding of 

 posterior lobe, 760. 



hemorrhage from vasoconstrictor ac- 

 tion of epiiiephrm in, 138. 



Kinetic theory of Crile of exophthal- 

 mic goiter, 313. 



Klebs, Edwin, monograph of, on acro- 

 megaly or gigaiitism, 56. 



Kopp, Johann Heiiirich (1830), "asth- 

 ma thymicum" and "thymus death" 

 in childhood, noted by, 55. 



Lacrimation, in tetany, 611. 

 Lactagog, mammary gland secretion as, 

 148. 



placental extract as, 147. 

 Lactation, in acromegaly, 839. 



as a factor in exophthalmic goiter, 

 308. 



effect of, on results of parathyroidec- 

 tomy, 527. 



effects on, of hypophysis feeding of 

 posterior lobe, 764. 



tetany associated with, 650. 



prognosis of, 672. 



Laryngeal paralysis, in exophthalmic 



goiter, 334. 

 Leg phenomenon in tetany, Pool's, 674. 



Schlesinger of Vienna, 601. 



his performance of, 602. 



See also Arm and leg phenomenon. 



Legallois (1801), observations of, 57. 

 Leucocytic formula, importance of, in 



hypothyroidism, 430. 

 Leukopenia, in exophthalmic goiter, 



351. 



Libido, and exophthalmic goiter, 335. 

 Ligaments, condition of, in hypothy- 

 roidism, 417. 

 Ligation of blood vessels, as method 



for decreasing function of organ, 



41. 

 Lipoids, presence of, in normal thyroid 



gland, 245. 

 Litten's phenomena, disturbance of, of 



autonomic origin, 334. 

 Liver, glycogen as "secretion interne" 



of, 59. 



glycogenic function of, 59. 

 Locomotor system, in hypothyroidism, 



416. 



symptoms of, associated with thy- 

 roid disease, 353. 



Loewi's epinephrin mydriasis test for 



hyperthyroidism, 498. 

 Loewi's sign, 323. 

 Lung, resemblance of thyroid gland to, 



269. 

 Lymphatic glands, enlargement of, in 



thyroid disease, 352. 



in hypothyroidism, 418. 

 Lymphatics, of hypophysis cerebri, 708. 



of the parathyroids, 502. 



of thyroid gland, 207. 

 Lymphatism of Heubner, 55. 



"Macrogenitosomia precox," doctrine 

 of, from pineal dysfunction, 67. 



Mammals, relation to growth and de- 

 velopment in, of hypophysis cerebri, 

 191. 



of sex glands, 198. 



of thyroid, 183. 



Mammary gland, organotherapy of, as 

 a lactagog, 148. 

 in uterine fibroids, 148. 



Mandible, in acromegaly, 831. 



Marburg, doctrine of "macrogtenito- 

 somia precox" established by (1907), 

 67. 



Marinesco-Roseo complement deviation 

 test for hyperthyroidism, 497. 



Masturbation, due to hypothyroidism, 

 411. 



Maternal administration of gland ex- 

 tracts, 38. 



Maternity tetany, 650. 



prognosis of, 671. 



