978 



INDEX 



Thyroid gland, halogens in, bearing of 



the general biochemistry of, on their 



presence in gland, 246. 

 iodin, compounds of and internal 



secretion, evidence connecting, 259. 

 forms of combination in gland, 



252. 

 Hunter's and Kendall's method 



of detection, 246. 

 normal content of, 248. 



percentage of, 246, 247. 



r- relationship between content of 



and thyroid activity, 262. 

 hematopoietic symptoms associated 



with disease of, blood, 350. 



hemorrhages, 352. 



lymphatic glands, 352. 



spleen, 352. 

 thymus, 352. 



hemorrhages of, 293. 



into the alveoli, causing cysts, 

 294. 



hyperplasia of, classification of, 273. 

 definition of, 273. 



primary, developmental stage, 



274. 



exhaustion atrophy, 276. 



involuntary stage, 275. 



regeneration and, as identical 



terms, 278. 

 secondary, developmental stage, 



277. 



exhaustion atrophy, 278. 

 involutionary or recovery 



stage, 278. 



hypertrophies and hyperplasias of, 

 272. 



scheme showing physiological and 



sequential relation of these changes, 

 273. 



in cretinic degeneration, pathology 

 of, 458. 



atrophic lesions, 461. 

 pathogenesis of goiter, 458. 



symptomatology of, goiter, 465. 



in hypothyroidism, atrophic change, 

 387; histopathological changes, 388; 

 hyperplastic processes, 387. 



inflammations of, 285. 



infectious theory of goiter, 285. 



thyroiditis, acute, 286. 



simple, 286. 



suppurative, 286. 



syphilitic, 286. 



tuberculous, 286. 



influence of, on metabolism, 237. 

 on stature, 26. 



Thyroid gland, internal secretion of, 

 231. 



channels for excretion of, 259. 



experimental feeding, 233, 234, 



235. 



iodin, 232. 



iodin compounds, evidence con- 

 necting, 259. 



iodothyrin, evidence for and 



against its being the internal secre- 

 tion of gland, 260. 



iodothyroglobulin, connection be- 

 tween, 261. 



nature and physiological action 



of, 232. 



- tests of, 259. 



acetonitril test of Reid Hunt, 

 260. 



metabolic method, 260. 



three definite functions of, defi- 

 nite action upon mobilization of car- 

 bohydrates, and retarding action 

 upon the combustion of sugar in the 

 blood, with resulting hyperglycemia, 

 476. 



forming basis for three most 



recent and valuable tests for thyroid 

 disorders, 475. 



specific stimulating action 



upon metabolic processes in the body, 

 causing increased or decreased me- 

 tabolism, 476. 



specific stimulating action 

 upon sympathetic portion of auto- 

 nomic system, rendering latter hyper- 

 sensitive to action of epinephrin, 475. 



thyroxin, 231. 



connection between, 261. 

 toxic effects of, 236. 



interrelation of hypophysis and, 194. 



iodin in, forms of combination of, 

 252. 



- Hunter's and Kendall's method 

 of detection of, 246. 



-percentage of, 246, 247. 



iodin compounds in, iodothyroglobu- 

 lin, 253, 261. 



"thyreoantitoxin," S. Frankl's, 



253. 



"thyroidin" (iodothyrin), Bau- 

 mann's, 253, 260. 



"thyroprotein," Notkin's, 253. 



- thyroxin, 254, 261. 



iodin content of, 248. 



changes induced by fall in, below 

 normal minimum, 273. 



distribution of, 252. 



