xxii LIST OF ILLUSTRATIONS 



SECTION XI 



THE INTERNAL SECRETION OF THE PANCREAS AND ITS 



DISORDERS 



The Anatomy, Embryology, Comparative Anatomy, and Histology of the 



Islands of Langerhans 



E. V. COWDRY 



FIGURE PAQE 



1. Islands of Langerhans in the pancreas of the guinea pig stained by 



injecting neutral red into the blood vessels 690 



2. Duct with system of delicate tubules connecting with the islands 



stained by injecting pyronin and neutral red into the blood vessels . 691 



3. Islet of Langerhans of a human pancreas fixed in Zenker's find and 



stained with hematoxylin and eosin illustrating apparent similarity 



of islet cells 693 



4. Islet of Langerhans of a guinea pig's pancreas fixed in chrome-sub- 



limate and stained with neutral gentian, revealing the true poly- 

 morphism of the cells 693 



5. Island of Langerhans in the pancreas prepared by Cajal's Uranium 



Nitrate Silver method which blackens the reticular apparatus . . 694 



The Pancreas as an Endocrin Gland 

 A. S. WARTHIN 



1. Chronic syphilitic pancreatitis with diabetes 725 



2. Chronic syphilitic pancreatitis with diabetes. Spirochaeta pallida 



found in heart and pancreas. No clinical signs of syphilis, Wasser- 

 mann negative 725 



3. Active area of plasma-cell infiltration in chronic syphilitic pancreatitis 



with diabetes 726 



4. Colony of SpirochaBta pallida, in edematous, infiltrated interlobular 



connective tissue . 726 



5. Atrophy and degeneration of acinar tissue with fibrosis of stroma in 



chronic syphilitic pancreatitis with diabetes 727 



6. Higher power view of acinar changes and interacinar fibrosis in 



chronic syphilitic pancreatitis. Healed, inactive area 727 



7. Atrophy of acini, increase of stroma, fatty infiltration of stroma, 



hyaline fibrosis of islets with characteristic pyknotic hyperchromatic 

 nuclei at periphery 728 



8. Hyaline fibroid islet from chronic syphilitic pancreatitis associated 



with diabetes 728 



9. Large hyaline fibroid islet with hyperchromatic and pyknotic cells at 



periphery 729 



10. New formations of lobules in chronic syphilitic pancreatitis with 



diabetes 729 



11. Adenomatous new-formation of lobules of acinar tissue in chronic 



syphilitic pancreatitis with diabetes. Dilated acinar lumen . . . 730 



12. High power view of new-formed acinar tissue seen in preceding figure. 



Dilated lumen with vacuolated cells and hyperchromatic nuclei . . 730 



