326 BENSON A. COHOE 



enzal cases. Wagner believes that the use of epinephrin in influenza is 

 indicated only when the condition is complicated with pneumonia, and the 

 lungs are rapidly invaded by a serous exudate. Jaksch-Wastenhorst states 

 that no benefit is to be derived from the use of epinephrin in pneumonia 

 and warns against its use. The future must reveal the true value of such 

 therapy in the hypoadrenia of acute infections. 



In the treatment of the purely functional forms of hypoadrenia, the 

 glandular extract has usually been employed. The use of epinephrin, over 

 prolonged periods, in this condition is clearly contra-indicated. Some 

 encouraging results have been described, especially in those forms of 

 neurasthenia in which suprarenal deficiency has been regarded as a causa- 

 tive factor. Some observers have preferred a pluriglandular form of ther- 

 apy, since the other endocrin glands are usually involved in this condi- 

 tion, and have, in many cases, administered several gland products, quite 

 empirically, without due consideration or knowledge of the functional 

 interrelation of the glands involved. Our knowledge of organotherapy is 

 as yet too limited to justify such indiscriminate endocrin polypharmacy. 

 To feed the body with hormones some of which are potent and toxic, and 

 allow the organism to select the deficient hormone, would appear to be 

 pseudo-science. 



Conclusion 



In conclusion it may be emphasized that most of the literature on 

 "hypoadrenia" betrays a profound ignorance (of modern suprarenal physi- 

 ology) upon the part of the writers and a remarkably cavalier attitude 

 toward the canons of logic. It is probably safe to forecast that, a decade 

 hence, much less will be heard of clinical suprarenal deficiency. 



