506 V. D. LESPINASSE 



on the lipped lip and pubic hair persisted. The voice again became in- 

 fantile, the penis shrunk and the sexual impulses ceased. In this con- 

 nection, I would call your attention to my own experimental work upon 

 cockerels, where a marked delay in the development of puberty was ob- 

 tained by removing portions of the testes. This delay was in direct pro- 

 portion to the amount of testicle removed. 



As an excellent example of a case of probably pure hyperfunction with- 

 out tumor, we can quote the following, reported by Dr. Robert Stone : 



The child is four years old. The boy is remarkably handsome, and 

 when stripped, presents a form of great beauty, which is, in fact, a mini- 

 ature model of a perfectly developed athlete. 



The condition of his muscular and osseous system is extraordinary; 

 the deltoids and other muscles of the arm, forearm, back, and thorax, 

 have the same relations to his height that those of a hard-laboring man 

 would have of a stature of six feet. The muscles of the thigh, gluteal 

 region, and leg, are perhaps better developed than those of the upper 

 extremity, but in nearly the same ratio to the height. 



If the child's face is concealed the examiner would declare his figure 

 to be that of a minature man, perfectly developed, and at least 21 years 

 of age. 



There seems to be little adipose tissue about him, the muscular promi- 

 nences being clear and well defined, as if produced by constant exercises 

 or hard labor. 



The growth of hair is distinct in the axilla, but by no means so marked 

 as that upon the pubes. As in very robust men, the lumbar and sacral 

 regions are covered with a thick down of dark hair. 



His height is now four feet one-quarter inch, and weight nearly 

 seventy pounds ; though his mother informs me he weighed seventy-five 

 pounds in the spring, and attributes his diminution to the great number of 

 lumbricoides which infest him. 



His penis is that of a well-developed man, measuring in a semi-flaccid 

 state four and a quarter inches in length, and in the state of perfect flac- 

 cidity three and a half inches. The prepuce is short, leaving exposed 

 a perfectly formed glans penis. I might state, also, that the papillae of 

 the corona glanclis are in a state of hypertrophy, being distinctly salient, 

 and exquisitely sensitive. The pubes are covered with a luxuriant gro<wth 

 of crisp, curling, dark-brown hair, as found in the adult state. In the 

 scrotum, presenting the appearance of the adult, are two firm, apparentlv 

 well-developed testicles, perhaps rather under the average size of those or- 

 gans in the adult. Independently of the penis, the development of these 

 alone would have been decidedly remarkable at that tender age. 



The 'spermatic cords are distinct, and under the finger give the im- 

 pression of perfect organs. 



Carefully examined from the neck down, the appearances are those 



