534 DAVID I. MACHT 



On the other hand, the experiments on the tadpoles, revealing a distinct 

 influence of prostate feeding on the growth and development of those 

 animals, and the data so far in hand concerning prostate feeding in 

 higher animals, speak very strongly in favor of an endocrin function of 

 the prostate gland. These experiments, together with those of Serralach 

 and Pares, would seem, in the author's opinion, to be the chief evidence in 

 favor of such a function. Macht and Bloom (1920) have also noted an 

 atrophy of the testes in rats in which the prostate glands were extirpated. 

 Inasmuch as the prostate gland can be completely excised in this animal, 

 the observations of these authors sustain the findings of Serralach and 

 Pares. The experiments with prostatectomized rats on the rope problem 

 (see above) are as yet incomplete, but nevertheless seem to. offer additional 

 evidence in favor of the production of an internal secretion by the prostate. 

 There seems, therefore, to be considerable evidence in favor of an endocrin 

 function of the prostate, and the subject warrants further investigation. 



