INFLUENCE OF OVARY OK GENERATIVE TRACT 627 



few cases, delayed puberty may be an indication of hypothyroidism, in 

 which case thyroid medication is of course indicated. 



The functional amenorrhea of later life is treated along similar lines. 

 The cases associated with hypopituitarism make up perhaps the largest 

 group. The organotherapy of these is considered at length elsewhere. 

 Thyroid, the various pituitary extracts (entire gland, anterior lobe and 

 posterior lobe), and ovarian extracts, have all been employed by various 

 workers. Polyglandular medication has achieved a wide vogue in the 

 treatment of such cases. 



In the cases which seem to be due chiefly or entirely to hypogenitalism, 



the rational treatment consists 

 in the administration of ovarian 

 extracts over a long period of 

 time. Some prefer extracts of 

 the entire ovary, some extracts 

 of the corpus luteum alone. The 

 results cannot be said to be 

 striking under either form of 

 medication. It is probable that 

 in these cases the hypogenital- 

 ism is practically always sec- 

 ondary, and that better results 

 are obtainable by the adminis- 

 tration of pituitary or thyroid 

 extracts, either alone or in com- 

 bination with the ovarian sub- 

 stances. 



Hypertrichosis in Relation 

 to the Ovary. From time to 

 time cases have been recorded 

 in which hypertrichosis, or ab- 

 normal hairy growth in various 

 regions, has been attributed to 



perversions . of ovarian function. A striking case was recently reported 

 by McAuliff (Fig. 4). His patient was a woman of 63, who presented 

 an excessive growth of grayish hair on the upper lip and chin and a 

 moderate amount on the cheeks. The woman suffered with a pelvic 

 tumor, which at operation proved to be a dermoid cyst of the left ovary. 

 Hypertrichosis has also been described in association with such anomalies 

 as uterus duplex (Hegar), uterus unicornis (Freund) and uterus infan- 

 tilis (Hildebrand, quoted by Hegar). It has also been attributed to such 

 acquired conditions as cystic ovaries (Roten, quoted by Scheuer), and 

 various tumors (Alberti). 



It is exceedingly doubtful, however, whether this symptom should be 



Fig. 4. Facial hypertrichosis, associated 

 with dermoid cyst of ovary (McAuliff). 



