T28 



A. S'. WARTHIN 



form of diabetes it is surprising that this so relatively rarely occurs. It is, 

 of course, possible that many cases of old syphilis are potential diabetics; 



Fig. 7. Atrophy of acini, increase of stroma, fatty infiltration of stroma, hyaline 

 fibrosis of islets with characteristic pyknotic hyperchromatic nuclei at periphery. 

 Chronic syphilitic pancreatitis with diabetes. 



and that any functional strain upon the pancreas may bring the functional 

 weakness above the clinical horizon. 



If pancreatitis is the essential pathology of pancreatic diabetes any 



Fig. 



_ 3. Hyaline fibroid islet from chronic syphilitic pancreatitis associated with 

 diabetes. Periphery of islet shows the hyperchromatic cells often mistaken for lymph- 

 ocytes. 



etiologic agent, infection, poisons, toxins, trauma, neoplasm, blocking of 

 ducts, etc., that may injure the pancreas to such an extent that functional 



