832 



PETER BASSOE 



peaked, which at necropsy proved to be hypernephroma. The hypophysis 

 was normal. These authors state that up to the time of their report (1914) 

 seventeen such cases with necropsy had been recorded, and that all cases 

 were alike. There was a tendency to development of male characteristics 



in girls and to an exaggeration 

 of male characteristics in boys. 

 All had died before the age of 

 sixteen years. 



To the sexual glands we re- 

 late Sacchi's case of a child 143 

 cm. tall at nine years with a 

 testicular tumor and to the 

 sexual glands and hypophysis 

 Neurath's (6) "Fettkinder," 

 which were both abnormally tall 

 and abnormally fat. 



The pineal gland was the 

 seat of a "psammosarcoma cysti- 

 cum" in the well-known case of 

 CEstreich and Slawyk. A boy, 

 normal up to the age of three 

 years, then began to grow rap- 

 idly, measuring 108 cm. at four 

 years. The bones and muscles 

 were strongly developed. The 

 penis was 9 cm. long, the pubic 

 hair 1 cm. long, and the mammae 

 hypertrophic. Choked disc and 

 convulsions pointed to the pres- 

 ence of a brain tumor which was 

 found to occupy part of the 

 third ventricle and to have orig- 

 inated in the pineal body. The 



thyroid, thymus, and hypophysis were normal. A similar case is reported 

 by Frankl-Hochwart in a boy of five years, whose size would have been 

 normal in a boy of nine years. 



A possible acromegalic type is briefly related by de Monchy in a child 

 17 months old and 93 cm. (36i/> in.) in length, with ocular signs of in- 

 creased intracranial pressure. The hands and feet were abnormally large, 

 and rontgenologic examination revealed that the frontal sinuses were 

 developed at this unusually early age ; but there was no definite proof of 

 sellar enlargement. 



Unclassifiable (poly glandular?) Cases. A remarkable case was re- 

 ported in 1903 by Hudovernig and Popovits and three years later by 



Fig. 18. Precocious boy of six years be- 

 side normal boy of fifteen years. (After Hudo- 

 vernig and Popovits.) 



