836 



PE'TER BASSOE 



and Jansco, and in the acromegalic giant of A chard and Loeper. Eran- 

 chini ha.d previously made similar studies in several cases of acromegaly 

 and the results in the two conditions are tabulated as follows : 



Acromegaly. 



In general good absorption of 

 nitrogen and fat by the digestive 

 apparatus. Strong retention of the 

 two substances. 



In half of the cases there was 

 alteration in the different nitrogen 

 groups with insufficiency of urea, 

 and increase of ammonia and 

 ammo acids. 



Altered splitting of the fats with 

 increase in neutral fats and choles- 

 terin and increased elimination of 

 fatty acids and soaps. 



Marked elimination of phospho- 

 rus, especially in the periods of 

 exacerbation of the disease and in 

 some cases inversion of the phos- 

 phatic formula. 



Xo alteration in the relation be- 

 tween neutral sulphur and acid 

 sulphur and consequently no altera- 

 tion in the oxidative processes. 



In one-third of the cases increase 

 in the sulphuric ethers, and in 

 nearly all cases notable increase in 

 indican, skatol and phenol. 



Retention of calcium more fre- 

 quent than its loss, but the variation 

 from day to day is remarkable. 



Retention of magnesium constant 

 in all cases. 



Gigantism. 



Same results. 



Same alterations and increase in 

 the precipitable nitrogen. 



Less accentuated loss of soaps 

 and less evident increase in neutral 

 fats ; notable insufficiency in fatty 

 acids and considerable increase in 

 cholesterin. 



Nearly normal elimination of 

 phosphorus and increase in the 

 earthy phosphates. 



Increase in neutral sulphur over 

 acid sulphur. 



Increase in sulphuric ethers and 

 in skatol, phenol and particularly 

 indican. 



Slight retention of calcium. 



Xot investigated. 



