MULTIGLANDTJLAR SYNDROMES 



809 



aches, produced MS will be discussed in the pathogenesis, are of a specific 

 type. They are invariably staled to be between the temples, the patient 

 indicating the locality by putting one index finger on each temple, directed 

 mesial ly. We have come to call them "pituitary headaches/' The vago- 



tonia present in many of the cases 

 frequently takes on the charac- 

 ter of hyperacidity of the gastric 

 juice with frequently symptoms 

 of gastric ulcer, spastic constipa- 

 tion, and eosinophilia. In the 

 third stage the symptoms of great 

 interest are the mental. In 

 many years' observation of pitui- 



Fig. 7. Height 6 feet, 2% inches; 

 feminine pubic hair; no hair on 

 face; musculature seems flabby; 

 feminine attributes. Blood sugar 

 and blood pressure still low, .with 

 headaches markedly diminishing. 

 Represents 3rd stage of syndrome. 



Fig. 8. Result of treatment of pa- 

 tient Fig. 7. Masculine pubic hair and 

 hair on thighs. Patient is now also 

 growing mustache and beard. 



tary disorders we have been frequently struck with the mental quips 

 of the hypopituitaric. He exhibits lack of inhibition of the emotions, be- 

 comes highly excitable on little cause, alternating with sluggishness ; fre- 

 quently has phobias and compulsions (one case was a true kleptomaniac), 

 shows frequently moral and sexual obliquities; and exhibition of pituitary 



