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HENRY G. BARBOUR 



In respect to enhancement of the cod liver oil effect calcium appeared 

 superior to phosphorus, which, when given with the oil, did not exhibit 

 any influence upon the calcium retention. 



Triacalcium phosphate Schloss found slightly better than calcium 

 acetate and equal in retention value to some other organic calcium prep- 

 arations. 



In the florid stages of rickets a high magnesium retention was noted. 

 This fell rapidly as the calcium retention increased, presumably owing to 

 medication. 



Gamble cites the following figures relative to calcium retention in 

 osteogenesis imperfecta : 



Author Age of patient Medication 



Bamburg & 

 Huldschinsky 



Bookman 

 Orgler 



3 months 



3 months 

 3 months 



Schabad 



MO 



years 



inone 

 cod liver oil -4- phosphorus 

 none 

 calcium lactate with food 

 none 

 r none 



cod liver oil -f- phosphorus 

 cod liver oil -4- phosphorus 



-4- calcium lactate 

 cod liver oil -f- phosphorus 



-f- calcium lactate 

 thyroid substance 



Herbst 



Retention of CaO 

 gram per day 

 0.042 

 0.089 

 0.054 

 0.402 



0.130-0.210 

 0.176 

 0.340 







0.338 



Fowler's solution 

 Fowler's solution 



(neg. balance) 

 (low or nega- 

 tive) 

 0.403 

 0.382 

 0.418 



Schabad (c) prefers arsenic to other medication in this condition, but 

 his results and those of others suggest that wide variations in calcium reten- 

 tion occur independently of medication. 



The conditions which govern calcium retention and assimilation n 

 pathological states are practically unknown. 



Calcium in Leprosy.' Recent investigations of Underbill, Honeij and 

 Bogert suggest that in leprosy administration of calcium may be of benefit 

 in retarding or arresting the progress of the characteristic bone chan 



Calcium in Tetany. Parathyroidectomy is followed by clonic con- 

 vulsions with fever. MacCallum during such an attack in a dog observec 

 the temperature increase from 39 to 43.2 C. The administration oi 

 calcium acetate stopped the convulsions in a few minutes and within oiu 

 half hour the temperature fell to 38.9. MacCallum and Voegtlin als 



