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JOSEPH C. ATJB 



inadequate blood flow and oxygen supply, and not to any other toxic 

 factor. When recovery from shock was obtained by the use of blood trans- 



Hours after AriaeslheTizaTion 



Fig. 2. An example of the respiratory exchange in the cat in experimentally 

 produced shock. Blood pressure ( Bl.Pr. ) was used as the index of the severity of 

 the condition. The calories used per hour (Cal.), Ventilation per 100 c.c. per minute 

 (Vent.) and Respiratory Quotient (R.Q. ) are shown graphically before and during the 

 course of severe shock. (From Aub.) 



fusion, and the blood pressure was raised above 80 or to a normal level, 

 the metabolism tended to return to the original rate. 



Chemical Changes in the Blood in Shock 



With the marked change in blood flow and the decreased metabolism 

 already described, and with the decreased urine output, due probably to 

 the reduced blood pressure, it is to be expected that there would be 

 marked chemical changes in the blood plasma. Govaerts first noted an 

 intense leukocytosis with large war wounds. Brodin and Saint Girons 

 judged this to be the response to the absorption of products produced 

 about the injured tissues. Duval and Grigaut studied the non-protein 



