DISTURBANCES OF CARBOHYDRATE METABOLISM 309 



very small difference, continued over a long time will, especially if com- 

 bined with overfeeding, produce a marked effect. 



A correspondingly greater increase in metabolism following the inges- 

 tion of glucose should be observed in hyperthyroidism and in those persons 

 who, in spite of adequate diet, remain unusually thin, without apparent 

 cause. 



This analogy has been presented and developed in the hope that it 

 may help to a better idea of how all disturbances in the metabolism of 

 glucose may be interrelated, and that it may lead to the formulation of new 

 problems, the solution of which will add to oiir knowledge of this very 

 interesting and important subject. 



