

METABOLISM IN NEPHKITIS 



375 



fluid after supper until the next breakfast and collects the urine for a 

 period beginning three hours after the evening meal until just before 

 breakfast the following morning, that is, for about ten hours, the quantity 

 of urine voided is usually 400 c.c. or less (Mosenthal(&), 1915), though it 

 may be as high as 750 c.c.'(Lyle and Sharlit, Mosenthal(c), 1918). An 

 amount between 400 and 750 c.c. may be regarded with suspicion ; a night 

 urine exceeding 750 c.c. is definitely pathological. A nycturia is found not 

 only in nephritis but in a number of other conditions, that must not be 

 confounded with Bright's disease : cystitis, hy pert ro phi ed prostate, ure- 

 thral stricture, pyelitis, anemia, polycystic kidney, elimination of edema, 

 diabetes or diabetes insipidus. Nocturnal polyuria occurs when renal 

 function is impaired for two reasons; first, and this is the more common 



TABLE 31 



RESULTS WITH THE TEST DAY FOB RENAL FUNCTION IN A CASE OF ACUTE NEPHRITIS 

 WITH EDEMA. THE EDEMA HAD PERSISTED FOB ABOUT FOUR MONTHS. ON THE 

 FIRST DAY THE VEBY SUDDEN CHANGE TO POLYURIA WITH A MUCH LOWERED SPE- 

 CIFIC GRAVITY MAY BE .NOTED. THE SUCCEEDING TEST SHOWS How THE ELIMINA- 

 TION OF EDEMA is CONTINUING. SUCH CHANGES ARE RESPONSIBLE FOB VEBY VARIA- 

 BLE RESULTS IN ACUTE NEPHRITIS; IT is OBVIOUS, HOWEVEB, THAT THEY ARE OF 

 GREAT IMPORTANCE. (Mosenthal, 1918) 



