Peptonuria and Prqteosuria 



JACOB KOSENBLOOM 



PITTSBURGH 



Peptonuria 



Peptones, the last stage in the digestion of protein before the amino 

 acids are produced, are rarely if ever found in the urine. Some have 

 claimed to have found them present together with proteose in pneumonia, 

 pulmonary tuberculosis, ulcer of the stomach and in women during the 

 puerperal period. In these cases, however, there are reasons to believe 

 that the substance present was not true peptone but was some type of 

 proteose. 



At present the condition presents nothing of clinical or therapeutic 

 interest. 



Proteosuria 



Both primary (protalbumose and heteroalbumose) and secondary 

 (deuteroalbumose) proteoses may be present in urine. They may occur 

 alone or associated with protein. The following distinct types of this con- 

 dition may be noted : 



1. Pyogenic: found in conditions associated with presence of pus 

 in the system, due to the dissolution of the pus cells and absorption of the 

 digested protein substance of the pus cells. It is observed in pneumonia 

 during the stage of resolution, in gangrenous conditions, in empyema, 

 bronchiectasis, abscess formation and in meningococcus infections. 



2. Hepatogenous : found in cases of marked disturbance in liver 

 function such as acute yellow atrophy, phosphorus poisoning, carcinoma, 

 cirrhosis and catarrhal jaundice. 



3. Enterogenous: found in cases of gastric and intestinal ulceration 

 and no doubt due to the breaking down of tissues. 



4. Hematogenous : found in scurvy, leukemia, purpura, dermatitis, 

 hemolytic poisons, pregnancy, dead fetus, psychoses and cancer, no doubt 

 brought about by the toxins. 



5. Febrile: found in all fevers due to the toxins of the disease and to 

 the septic processes associated with the disease. 



483 



