532 



KAHN ATs T D ROSENBLOOM 



content of the urine was also increased. Gross reported that cystein is 

 very soon changed to cystin. 



Blum(&) fed cystin to dogs and rabbits and he found that there was a 

 marked increase in the sulphate elimination in the urine. Subcutaneous 

 injection of 1.1 gm. cystin did not cause any cystin excretion in the 

 urine. The administration of cystin intravenously in the peripheral 

 circulation produced a marked output of cystin in the urine in four 

 hours. But upon injecting the cystin into the mesenteric vein, no cystin 

 appeared in the urine, and there was no increase in the ethereal sulphate 

 output : 



Dog 1 



Dog 2 



Dog 3 



Dog, wt. 9 K 

 Received 1.1 gm. Cystin in 90 c. c. 0.0075% Na 2 CO s Solution Subcutaneously 



