METABOLISM IN DISEASES OF BONES AND JOINTS 741 



TABLE 10 



RATIO OF CA : MG IN DRIED BONE, NORMAL AND OSTEOMALACIA 



TABLE 11 



RATIO OF CA : MG IN BONE ASH (NORMAL AND OSTEOMALACIA) 



Ratio of Calcium to Magnesium 



It is interesting to note that the same great increase in magnesium 

 was observed in a case of artificial Osteomalacia, induced in a rabbit by 

 the repeated injection of glucose (Badolle). With a fall of about twenty 

 per cent in the calcium content of the bone, there was a five-fold increase 

 in the magnesium (Table 12). 



TABLE 12 

 DISPROPORTIONATE INCREASE OF MAGNESIUM IN BONE IN ARTIFICIAL OSTEOMALACIA 



The increase in magnesium strongly suggests that this element is 

 used in part to supply the deficiency in calcium. The quite opposite 



