METABOLISM IN DISEASES OF BONES AND JOINTS 745 



Corresponding with the increased magnesium content of osteomalacia 

 bone, we find that the body is retaining magnesium (Table 18). 



TABLE 18 



MAGNESIUM METABOLISM IN OSTEOMALACIA 



In the case of sulphur, again, as in the case of magnesium, we find a 

 retention corresponding to the increased amount of the element found in 

 the bone (Table 19). 



TABLE 19 



SULPHUR METABOLISM IN OSTEOMALACIA 



The question arises: Are the amounts of elements gained and lost 

 in these studies outside the limits to be expected in a normal case ? Are 

 the figures significant ? 



Consider, for example, the ten-day experiment of McCrudden and 

 Fales(6) (Table 20), the case in which the daily loss of calcium was least. 



TABLE 20 



TEN DAY METABOLISM OBSERVATION' IN OSTEOMALACIA 



