7G2 



FRANCIS H. McORUDDEN 



Fig. 1 shows one of the bony tumors, 

 rarifaction of the bone. 



Fig. 2 shows an example of the 



The patient, an unmarried woman of forty-two, dates her illness to 1891, when she 

 noticed a hard, painless nodule about the size of a bean on the right side of her lower 

 jaw. Six months later, the growth, which had by then increased to the size of a hen's 

 egg, together with a piece of the jaw, was removed. In 1895 she began to have difficulty 

 in walking; her ankles would "bend in and out on walking, as if they were made of 



Fig. 1. 



rubber." In the fall of the year, small, hard painless nodules were noticed on her 

 shin bones. The largest, on the left, was about the size of a walnut. In 1898, while 

 riding on a tricycle, she fell and fractured her right thigh, but it caused her very 

 little pain. During the seven weeks that she was laid up with this fractured thigh, 

 she had an attack of renal colic, and three weeks later passed several small, gray 

 stones. At intervals of six to eight months for the next six years, she had attacks 

 of renal colic; and about three weeks after each attack she would usually pass a stone 

 about the size of a pea. Since about 1905, a hard, painless growth near the lower edge 

 of the spine has been gradually enlarging. In 1908. a bony growth, which has since 

 caused difficulty in breathing, appeared in the right nostril. In 1909, she noticed 

 small, hard nodules on her forehead. About this time, in shaking hands with a friend, 

 the second metacarpal bone of the right hand became fractured. In August, 1910, while 

 washing her hands, she dislocated the terminal phalanx of the left index finger. By 

 1911, she had become bedridden on account of increasing stiffness and weakness. At 

 this time she felt pain only when moving about or being handled. 



