774 



FRANCIS H. MoCBTJDDEN 



Table 30 shows the result of a nine-day metabolism observation made 

 in a case of hypertrophic arthritis (Goldthwait, Painter and Osgood). 



TABLE 30 



METABOLISM IN HYPEBTROPHIC ARTHRITIS 



The striking features in this table are the loss of calcium and retention 

 of magnesium and sulphur, findings similar to those in osteomalacia. A 

 closer examination of the data shows fairly normal figures for the amount 

 of calcium excreted through the urine, but high figures for the calcium 

 excretion through the feces. The amount of calcium in the feces is about 

 96 per cent of that in the food. Normal figures are very variable, 65 to 78 

 per cent (Goldthwait, Painter and Osgood), but do not ordinarily reach 

 the figures found in this case. 



The amount of phosphate in the feces is about equal to that in the 

 urine. Normal figures, though very variable, show much less phosphate 

 in the feces than in the urine about half as much, in our normal cases 

 (Goldthwait, Painter and Osgood). In this case of hypertrophic arthritis, 

 the urine contains only half as much phosphate as the food; the normal 

 amount is much more seventy per cent in our cases (Goldthwait, Painter 

 and Osgood). 



It has been shown that administration of calcium salts causes an 

 increased excretion of phosphate in the feces. In accordance with the 

 experimental data, the loss of phosphate through the feces in this case 

 could, therefore, be considered secondary to the loss of calcium. The 

 reverse is, of course, theoretically possible, but in view of the fact that 



