820 



FRANCIS H. MoCKUDBEN 



TABLE 10 

 FAT IN THE FECES IN INTESTINAL INFANTILISM 



The occasional occurrence of acetonuria suggested the possibility of 

 acidosis. But the low ammonia excretion (see Tables 3 and 4) shows that 

 there is no acidosis. 



There is nothing in the evidence to indicate any abnormality in the 

 digestion, absorption, or intermediary metabolism of protein, fat, or 

 carbohydrate, or in the metabolism of energy. There is nothing to indi- 

 cate starvation or partial starvation in the ordinary sense of the word; 

 the nutrition of the soft tissues appears to be normal. 



One of the striking features of the disease is the bone fragility. The 

 patient F. S. suffered bone fractures as the result of very slight trauma. 

 Rontgenographic examination showed that the cortex of all the bones is 

 very thin and rarefied (McCrudden(d)). * 



The accompanying plates show prints of x-ray plates of the tibia and 

 carpal bones of one hand in the cases of F. S. and F. H., two cases of in- 

 testinal infantilism ; and similar prints from dwarfs of three other types 

 and one normal boy. The thin and rarefied cortex in the cases of infantil- 

 ism can be made out even in the prints, though not of course as clearly 

 as in the originals. The difference cannot be ascribed to differences in 

 technique in making the rb'ntgenograms ; many plates were made at differ- 

 ent times, and the results found were constant. 



These bony changes, together with a very low calcium content of the 

 urine, made complete balance studies of the mineral metabolism seem 

 desirable. 



Tables 11 and 12 show the results of balance studies in two cases of 

 intestinal infantilism. For comparison, Tables 13, 14 and 15 show the 

 results in dwarfs of three other types; and Table 16 those of a normal 

 boy (McCrudden(c?), McCrudden and Fales(&)). 



